Bradykinesia and impairment of EEG desynchronization in Parkinson's disease
Identifieur interne : 004D97 ( Main/Exploration ); précédent : 004D96; suivant : 004D98Bradykinesia and impairment of EEG desynchronization in Parkinson's disease
Auteurs : Peter Brown [Royaume-Uni] ; C. David Marsden [Royaume-Uni]Source :
- Movement Disorders [ 0885-3185 ] ; 1999-05.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Adulte.
English descriptors
- KwdEn :
- Adult, Aged, Alpha rhythm, Basal Ganglia (physiopathology), Beta rhythm, Body movement, Bradykinesia, Cortical Synchronization, Desynchronization, Electroencephalography, Exploration, Female, Humans, Hypokinesia (diagnosis), Hypokinesia (etiology), Hypokinesia (physiopathology), Male, Middle Aged, Motricity, Parkinson Disease (complications), Parkinson Disease (physiopathology), Parkinson disease, Parkinson's disease, Performance evaluation, Severity of Illness Index.
- MESH :
- complications : Parkinson Disease.
- diagnosis : Hypokinesia.
- etiology : Hypokinesia.
- physiopathology : Basal Ganglia, Hypokinesia, Parkinson Disease.
- Aged, Cortical Synchronization, Electroencephalography, Female, Humans, Male, Middle Aged, Severity of Illness Index.
Abstract
It has been suggested that the basal ganglia control the release of cortical elements from low‐frequency rhythmic idling activity during voluntary movement.1 This hypothesis was tested by recording the local idling rhythms of the motor cortex, the alpha and beta rhythms, in 12 untreated and treated patients with Parkinson's disease as they moved a wrist. Recordings were made after overnight withdrawal of medication and again 1 hr after levodopa. The treatment‐related attenuation of the alpha and beta rhythms picked up over the cortical motor areas contralateral to the active arm correlated with the improvement in size and speed of movement effected by levodopa. The distribution and degree of attenuation depended on the complexity of the task. These results demonstrate for the first time a specific effect of levodopa on the organization of motor cortical activity in the frequency domain, an effect that correlates with improvements in bradykinesia.
Url:
DOI: 10.1002/1531-8257(199905)14:3<423::AID-MDS1006>3.0.CO;2-V
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001C01
- to stream Istex, to step Curation: 001C01
- to stream Istex, to step Checkpoint: 003564
- to stream Main, to step Merge: 007A96
- to stream PascalFrancis, to step Corpus: 002E04
- to stream PascalFrancis, to step Curation: 003A20
- to stream PascalFrancis, to step Checkpoint: 002E59
- to stream Main, to step Merge: 007D08
- to stream PubMed, to step Corpus: 004209
- to stream PubMed, to step Curation: 004209
- to stream PubMed, to step Checkpoint: 004261
- to stream Ncbi, to step Merge: 000043
- to stream Ncbi, to step Curation: 000043
- to stream Ncbi, to step Checkpoint: 000043
- to stream Main, to step Merge: 007868
- to stream Main, to step Curation: 004D97
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Bradykinesia and impairment of EEG desynchronization in Parkinson's disease</title>
<author><name sortKey="Brown, Peter" sort="Brown, Peter" uniqKey="Brown P" first="Peter" last="Brown">Peter Brown</name>
</author>
<author><name sortKey="Marsden, C David" sort="Marsden, C David" uniqKey="Marsden C" first="C. David" last="Marsden">C. David Marsden</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:A9595FF88EC25C1CB5DDECC8212C6F50B11BF439</idno>
<date when="1999" year="1999">1999</date>
<idno type="doi">10.1002/1531-8257(199905)14:3<423::AID-MDS1006>3.0.CO;2-V</idno>
<idno type="url">https://api.istex.fr/document/A9595FF88EC25C1CB5DDECC8212C6F50B11BF439/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001C01</idno>
<idno type="wicri:Area/Istex/Curation">001C01</idno>
<idno type="wicri:Area/Istex/Checkpoint">003564</idno>
<idno type="wicri:doubleKey">0885-3185:1999:Brown P:bradykinesia:and:impairment</idno>
<idno type="wicri:Area/Main/Merge">007A96</idno>
<idno type="wicri:source">INIST</idno>
<idno type="RBID">Pascal:99-0271321</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">002E04</idno>
<idno type="wicri:Area/PascalFrancis/Curation">003A20</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">002E59</idno>
<idno type="wicri:doubleKey">0885-3185:1999:Brown P:bradykinesia:and:impairment</idno>
<idno type="wicri:Area/Main/Merge">007D08</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:10348464</idno>
<idno type="wicri:Area/PubMed/Corpus">004209</idno>
<idno type="wicri:Area/PubMed/Curation">004209</idno>
<idno type="wicri:Area/PubMed/Checkpoint">004261</idno>
<idno type="wicri:Area/Ncbi/Merge">000043</idno>
<idno type="wicri:Area/Ncbi/Curation">000043</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000043</idno>
<idno type="wicri:doubleKey">0885-3185:1999:Brown P:bradykinesia:and:impairment</idno>
<idno type="wicri:Area/Main/Merge">007868</idno>
<idno type="wicri:Area/Main/Curation">004D97</idno>
<idno type="wicri:Area/Main/Exploration">004D97</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Bradykinesia and impairment of EEG desynchronization in Parkinson's disease</title>
<author><name sortKey="Brown, Peter" sort="Brown, Peter" uniqKey="Brown P" first="Peter" last="Brown">Peter Brown</name>
<affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Human Movement and Balance Unit, Institute of Neurology and National Hospital for Neurology and Neurosurgery, Queen Square, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Marsden, C David" sort="Marsden, C David" uniqKey="Marsden C" first="C. David" last="Marsden">C. David Marsden</name>
<affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>MRC Human Movement and Balance Unit, Institute of Neurology and National Hospital for Neurology and Neurosurgery, Queen Square, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="sub">Official Journal of the Movement Disorder Society</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>John Wiley & Sons, Inc.</publisher>
<pubPlace>New York</pubPlace>
<date type="published" when="1999-05">1999-05</date>
<biblScope unit="vol">14</biblScope>
<biblScope unit="issue">3</biblScope>
<biblScope unit="page" from="423">423</biblScope>
<biblScope unit="page" to="429">429</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">A9595FF88EC25C1CB5DDECC8212C6F50B11BF439</idno>
<idno type="DOI">10.1002/1531-8257(199905)14:3<423::AID-MDS1006>3.0.CO;2-V</idno>
<idno type="ArticleID">MDS1006</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Alpha rhythm</term>
<term>Basal Ganglia (physiopathology)</term>
<term>Beta rhythm</term>
<term>Body movement</term>
<term>Bradykinesia</term>
<term>Cortical Synchronization</term>
<term>Desynchronization</term>
<term>Electroencephalography</term>
<term>Exploration</term>
<term>Female</term>
<term>Humans</term>
<term>Hypokinesia (diagnosis)</term>
<term>Hypokinesia (etiology)</term>
<term>Hypokinesia (physiopathology)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Motricity</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinson disease</term>
<term>Parkinson's disease</term>
<term>Performance evaluation</term>
<term>Severity of Illness Index</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Hypokinesia</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Hypokinesia</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Basal Ganglia</term>
<term>Hypokinesia</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Cortical Synchronization</term>
<term>Electroencephalography</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Severity of Illness Index</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Adulte</term>
<term>Bradykinésie</term>
<term>Electroencéphalographie</term>
<term>Evaluation performance</term>
<term>Exploration</term>
<term>Motricité</term>
<term>Mouvement corporel</term>
<term>Parkinson maladie</term>
<term>Rythme alpha</term>
<term>Rythme bêta</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Adulte</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">It has been suggested that the basal ganglia control the release of cortical elements from low‐frequency rhythmic idling activity during voluntary movement.1 This hypothesis was tested by recording the local idling rhythms of the motor cortex, the alpha and beta rhythms, in 12 untreated and treated patients with Parkinson's disease as they moved a wrist. Recordings were made after overnight withdrawal of medication and again 1 hr after levodopa. The treatment‐related attenuation of the alpha and beta rhythms picked up over the cortical motor areas contralateral to the active arm correlated with the improvement in size and speed of movement effected by levodopa. The distribution and degree of attenuation depended on the complexity of the task. These results demonstrate for the first time a specific effect of levodopa on the organization of motor cortical activity in the frequency domain, an effect that correlates with improvements in bradykinesia.</div>
</front>
</TEI>
<affiliations><list><country><li>Royaume-Uni</li>
</country>
<region><li>Angleterre</li>
<li>Grand Londres</li>
</region>
<settlement><li>Londres</li>
</settlement>
</list>
<tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Brown, Peter" sort="Brown, Peter" uniqKey="Brown P" first="Peter" last="Brown">Peter Brown</name>
</region>
<name sortKey="Marsden, C David" sort="Marsden, C David" uniqKey="Marsden C" first="C. David" last="Marsden">C. David Marsden</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004D97 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 004D97 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= Main |étape= Exploration |type= RBID |clé= ISTEX:A9595FF88EC25C1CB5DDECC8212C6F50B11BF439 |texte= Bradykinesia and impairment of EEG desynchronization in Parkinson's disease }}
This area was generated with Dilib version V0.6.23. |